LulzBot Bio

FRESH Certified 3D Bioprinter

By LulzBot

LulzBot Bio

FRESH Certified 3D Bioprinter

By LulzBot

7000.00

Orders placed now are expected to ship starting December, 2019.
Free Shipping in the US
One-Year Warranty
Made in the USA
FRESH certified for advanced bioprinting capabilities

The LulzBot Bio is a FRESH certified bioprinter ready for use with bioinks, unmodified collagen, and other soft materials for pharmaceutical/cosmetic testing, tissue engineering, and regenerative medicine.

FRESH Certified Edition includes 10g of LifeSupport™ support material (4 x2.5g vials). See Package Contents section below for details.

NOTE: 3D Universe is authorized to sell this product in the United States of America, only.

The LulzBot Bio is a FRESH certified bioprinter ready for use with bioinks, unmodified collagen, and other soft materials for pharmaceutical/cosmetic testing, tissue engineering, and regenerative medicine.

Overview


Introducing the LulzBot Bio

The LulzBot Bio combines versatility with exceptional print quality in a compact and easy-to-use bioprinter. Certified for FRESH printing, the Bio includes everything you need to get started printing bioinks, unmodified collagen, and other soft materials. With an Open Source design and less than an hour of out-of-the-box setup time, the Bio’s capabilities can grow as fast as your innovation.

Bioprinting is revolutionizing pharmaceutical development, cosmetic testing, tissue engineering, and regenerative medicine. 3D bioprinted tissues can be used to mimic in vivo conditions, enabling organizations to better predict efficacy and toxicology of potential drugs early on in the drug discovery process.

Check out the video overview to learn more.


FRESH Certified for Advanced Bioprinting

The LulzBot Bio is FRESH certified, which means it's designed to take advantage of the most advanced bioprinting method currently available.

FRESH (Freeform Reversible Embedding of Suspended Hydrogels) allows for 3D printing of bioinks, unmodified collagen, and other soft materials. By printing into a suspension of support material (LifeSupport), these soft structures can be printed in ways never before possible.

This bioprinting approach has been used with great success by leading medical researchers. See the following publications for details:

Check out this video to see how the LifeSupport material is prepared.


Syring Pump Extruder

The syringe pump extruder design allows for precise control of material extrusion, enabling printing of high-detail objects in a wide range of materials with varying viscosities.

Note: The syringe pump extruder uses Hamilton Gas Tight 1000 Series Syringes (81420, 81520, and 81620) with X-Style Plunger and Luer Lock termination. The Bio will come with one Hamilton 2.5 mL Gastight Syringe Model 1002 TLL as well as 3 different size syringe collars for 2.5 ml, 5 ml and 10 ml glass syringes.


Easy-to-Use Interface

The Bio features a 4.5” glove-friendly touch screen and SD card slot for easy operation without the need to be tethered to a computer.

All of the printer's functions can be accessed via an intuitive touch panel which provides graphical indications for easy operation of the LulzBot Bio.


Heated Bed

The heated bed makes it easy to dissolve the LifeSupport material after your print is finished. Just leave the heated bed at room temperature while printing, then heat it to body temperature to easily melt away the LifeSupport suspension material once your print is complete.


A Vast Array of Exciting Applications

The open source design of the FRESH Certified LulzBot Bio opens up a world of exciting possibilities across a range of industries. Here are just some of the possible use cases:

  • Pharmaceutical & cosmetic testing
    • In vitro (in a test tube) testing aims to reduce failure rate (currently 90%+) of bringing drugs to market (costs ~$2.5b in 2018) by testing on bioprinted tissues in pre-clinical testing. The goal is to reduce failure when moving to phase 3 (clinical) trials (estimated 50% failure rate in clinical trials).
    • Can be used to recreate physiology to study disease.
    • Testing on kidney and liver cells are of particular importance.
  • Tissue Engineering – The practice of combining scaffolds, cells, and biologically active molecules into functional tissues.
    • Long term goal of bioprinting human organs.
  • Regenerative Medicine – The process of replacing, engineering or regenerating human cells, tissues or organs to restore or establish normal function.
  • Education – The bio is expected to be extremely impactful for teaching life sciences in K-12.

Extensive Material Options

The LulzBot Bio’s open materials system includes ready-to-print profiles for alginate and unmodified collagen. With a configurable syringe pump system and extrusion settings, the Bio is easily adjustable for new materials and processes.


Best Available Desktop 3D Bio Printer

No other desktop 3D bioprinter can match the value and capabilities of the LulzBot Bio:

  • Able to print unmodified collagen and other soft materials. Other bioprinting techniques often require chemical alteration or mixing of materials to enable / improve ‘printability’.
  • Hardware / software is easily configurable for new materials and processes.
  • Open material format. No proprietary materials.
  • More affordable than most market options.
  • Bigger maximum print area than most competitors. The compact design easily fits within laminar flow cabinets or tissue culture hoods.
  • LulzBot has a long standing reputation for exceptional print quality. Print quality is said to match or exceed $100k+ machines.
    • Some of the best print quality for FFF style bioprinters.
    • Improved print quality by an order of an magnitude over Fresh 1.0 (250 μm to 20 μm)
  • Comes with a generous supply (50g) of Sodium Alginate (this material alone would cost up to $32,000 from other companies)
  • Syringe pump system enables printing of highly intricate structures such as blood vessels and artery trees
    • Better control of stopping / retraction which reduces oozing.
    • Pneumatic systems only have positive pressure and near zero pressure.
    • For pneumatic systems, the pressure required to extrude materials is not linear and variable based on the amount of material in the system.
    • It is speculated that some of the pneumatic systems on the market lack adequate pressure to dispense highly viscous materials.
  • Syringe pump system enables printing of highly intricate structures such as blood vessels and artery trees
    • Better control of stopping / retraction which reduces oozing.
    • Pneumatic systems only have positive pressure and near zero pressure.
    • For pneumatic systems, the pressure required to extrude materials is not linear and variable based on the amount of material in the system.
    • It is speculated that some of the pneumatic systems on the market lack adequate pressure to dispense highly viscous materials.

Package Contents

LulzBot Bio

Package Contents

  • LulzBot Bio
  • Power Cord
  • USB Cord
  • SD Card
  • Quick Start Guide
  • Bio Tool Bag
  • 50g Sodium Alginate
  • 1g Alcian Blue 8GX – Water soluble cationic dye
  • Calcium Chloride- 60 cc
  • Hamilton 2.5 mL Gastight Syringe Model 1002 TLL
  • Box of needles (50pk) - 25 gauge
  • Box of needles (50pk) - 30 gauge
  • 2 Syringe thumb screws
  • 35mm Petri dish
  • 60 mm Petri Dish
  • Glass 50mL Crystallizing Dish
  • 1 oz Vacuum grease
  • Allen wrench set
  • Long nose pliers
  • Ruler
  • Tweezers
  • 3 different size syringe collars for 2.5 ml, 5 ml and 10 ml glass syringes.
  • 10 ml Disposable syringe x 2
  • Collar kit for disposable syringe
  • Male Luer lock Plug x 2
  • Female Luer adapter x 2

LulzBot Bio FRESH Certified Edition

Package Contents

  • All of the above, plus 10g of LifeSupport™ support material (4 x2.5g vials)

Specifications

LulzBot Bio

Specifications

Printing

Print Technology: Fluid Deposition Fabrication

Print Head: Syringe Pump Extruder

Maximum Print Area: 160mm x 160mm x 89mm1 (6.30in x 6.30in x 3.5in1)

Minimum Layer Resolution: 50 µm2

Minimum Positive Feature Size: 80 µm3

Calculated XYZ Positional Resolution: 10, 10, 5 µm

Recommended Operating Temperature: From 5°C to 40°C (41°F to 104°F)

Operating Footprint: 45.7cm x 40.6cm (18in x 16in)

Connectivity: USB Serial and SD Card

Print Surface: Heated Borosilicate Glass

Maximum Print Surface Temperature: Up to 120°C (248°F)

Print Surface Heat Up Time: 23°C to 60°C (73°F to 140°F) in 97 seconds

Interface: Glove-Friendly 4.5” Touch-Screen

Materials: Open materials system including ready-to-print profiles for alginate and collagen.

Software

Operating System Compatibility: GNU/Linux, Mac, Windows

Recommended Software: Cura LulzBot Edition (Latest Version)

Firmware: Marlin

Supported File Types: .stl, .obj, .g, .gcode, .x3d, .3mf

Electrical

Power Requirements: 100VAC-240VAC, 50Hz-60Hz, 3.2A max

Output: 24VDC

Power Supply: IEC cord, C13 to region-specific connector

Safety & Compliance

Certifications: UL (Pending), FCC, CE, WEEE, CSA, RCM, OSHWA


Download the full specifications sheet here.

Accessories

LulzBot Bio

ACCESSORIES


LulzBot Bio accessories are coming soon. Please check back.


Helpful Resources

Support Resources

For general usage questions, contact 3D Universe:

Email: support@3duniverse.org
Phone: 800-689-4344

For hardware-related support, contact LulzBot Support:

Web: https://www.lulzbot.com/support
Email: Support@LulzBot.com
Phone: +1-970-377-1111

 

Helpful Videos

3D Printing Resources

Repositories for 3D Bioprinting Models:

Software:


Why Buy From 3D Universe?

Fast, Reliable Shipping

Most orders for in-stock items ship within one business day.

Secure Online Checkout

3D Universe accepts all major credit cards, as well as online payment methods like PayPal, Apple Pay, Amazon Pay, and Google Pay.

Purchase Orders Accepted

Purchase orders are accepted from qualifying organizations with Net 30 terms for orders of $200 or more. Email us for more information.

Excellent Customer Support

Call us at 800-689-4344 or email us if you need any assistance!


Get the Quality Filament You Need

Nothing will impact your 3D printing results like the kind of filament you use. Good filament is highly consistent in diameter, is wound evenly onto the spool with just the right amount of tension, and will not tangle when being unwound. 3D Universe offers a wide range of high-quality filaments to choose from. We provide a 100% satisfaction guarantee on all filament we sell. If you have any problems, just send back the unused portion of the spool for a full refund. Check out our filament collection...

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